2024 Pico question examples women

The framework is actually divided into four major elements. A good clinical question will address most, if not all, aspects of the PICO nursing questions. The following are the parameters defined by PICO (T) when it comes to designing of clinical questions: P: Patient, Problem, Population. I: Intervention.. Pressed paper shop

Aug 9, 2023 · Question Type & Study Design. Some study designs are better suited to answer certain types of questions. Identifying the clinical domain your question falls under can help determine what study designs to look for in order to find the best, most suitable evidence. Systematic Reviews and Meta-Analyses are always preferred. Note: The question may also appear as: What is the effectiveness of early ambulation, compared to bed rest, on decreasing post-op DVTs in adult patients with total hip replacements. Meaning PICO Question: How do pregnant women (P) newly diagnosed with diabetes (I) experience reporting their blood sugar levels (O) to their healthcare providers? <<The PICO question in this paper seeked to answer the question: in adult patients without celiac disease or gluten sensitivities, is GF food correlated with higher type 2 diabetes or CVD risk? The question was underpinned by a research study showing an inverse relationship between gluten consumption and type 2 diabetes rates.Jul 26, 2023 · [Examples modified and drawn from Glasper, A. and Rees, C. (2013) How to Write Your Nursing Dissertation] The following examples may help you put PICO into practice. Suggestions in the brackets are just extra ideas for what you might want to consider. 1) Isobel is a 45 year old woman who asks you for advice on natural ways of resolving her ... This is among the perfect PICOT question examples for falls. 2. The Prognosis or the Prediction. These questions are used in determining the possible complications that arise from a particular condition or the clinical course over a specific time frame. An example of an intervention PICOT questions is as follows:“The question needs to identify the patient or population we intend to study, the intervention or treatment we plan to use, the comparison of one intervention to another (if applicable) and the outcome we anticipate,” Kathy A. Jensen, MHA, RN, wrote in EBSCO Health’s whitepaper, “7 Steps To The Perfect Pico Search.” “Once a well ... Level of Evidence What is a PICO Question? PICO is an acronym used for exploring clinical questions. It serves as a framework for evidence-based practice. P (Problem and Population) What health problem is your selected intervention intended to solve? Identify what population of people will benefit the most from your chosen intervention.PICOT is different from a standard research question because it is a clinical question. It is composed of various elements that create a framework for research that typical research questions do not usually have. The goal or purpose of PICOT is to ultimately intervene in someone's healthcare. Focus on prevention.Background questions ask for general knowledge about an illness, disease, condition, process or thing. These types of questions typically ask who, what, where, when, how & why about things like a disorder, test, or treatment, etc. For example. How overweight is a woman to be considered slightly obese? What are the clinical manifestations of ...Aug 29, 2023 · Concepts from the PICO(T) question are used to construct a comprehensive database search strategy with search terms describing each relevant component of the PICO(T). Relevant elements of your PICO(T) question can be used to develop an initial list of keywords (including synonyms) to use in a database search. The most important parts of a PICO ... Question 1. Question 2. Question 3. Population. Children <6 years of age. AND. Diagnosed with ADHD or at risk for ADHD or diagnosed with DBD (including ODD and CD by DSM) ≥6 years of age (subjects <6 years are described in Question 1) Diagnosed with ADHD by the DSM or ICD criteria that was in use at the time of the study or of the publication.It is important to note that there are different types or categories of PICOT questions. The category of your question can at times dictate the types of evidence that you are searching for. Determine in which category your question would best fit. Use the template to help you word it succinctly and correctly.PICOT: This evidence-based project answered the following question: In rehabilitation patients, what is the effect of a nurse-driven protocol (NDP) CAUTI bundle on the number of indwelling urinary catheter-related infections, compared to the current practice, over a 12-week time period? EvidenceSep 21, 2019 · The list of PICOT question examples will be incomplete if we didnâ&#x20AC;&#x2122;t mention a question about severe malnutrition. 23. Can antibiotics prevent death and sequelae in kids ... Jul 6, 2023 · Have two essential components: Example: What causes migraines? or How often should women over the age of 40 have a mammogram? A question root (who, what, when, etc.) with a verb A disorder, test, treatment, or other aspect of healthcare The background question is usually asked because of the need for basic information. The PICO question in this paper seeked to answer the question: in adult patients without celiac disease or gluten sensitivities, is GF food correlated with higher type 2 diabetes or CVD risk? The question was underpinned by a research study showing an inverse relationship between gluten consumption and type 2 diabetes rates. Aug 16, 2023 · 2. Foreground questions are specific knowledge questions . that affect clinical decisions and ; include a broad range of biological, psychological, and sociological issues. Foreground questions are best suited to the PICO model as it captures the essential elements of your information need to help translate that question into a search query. To ... 13 examples of PICOT Questions. PICOT question examples emergency nursing. PICOT question examples pregnancy. PICOT question examples hypertension. PICOT question nurse burnout. PICOT question medication errors. PICOT questions for icu nurses. PICOT question childhood obesity.PICOT QUESTION PAPER: INFERTILITY Significance to Nursing In nursing, fertility is a process that begins from the second a woman states she is attempting to become pregnant but is having difficulty. Nurses are also educators, so a main component to treating a woman who has fertility issues is to make them aware of their options and issues. PICOT: This evidence-based project answered the following question: In rehabilitation patients, what is the effect of a nurse-driven protocol (NDP) CAUTI bundle on the number of indwelling urinary catheter-related infections, compared to the current practice, over a 12-week time period? Evidence PICOT: This evidence-based project answered the following question: In rehabilitation patients, what is the effect of a nurse-driven protocol (NDP) CAUTI bundle on the number of indwelling urinary catheter-related infections, compared to the current practice, over a 12-week time period? Evidence Example 2. You are working with a recent stroke patient who is having balance issues and you are considering using virtual reality in their therapy. P = recent stroke, balance issues. I = virtual reality. C = no virtual reality. O = improved balance "In recent stroke patients, how does using virtual reality affect or improve balance?" Example 3[Examples modified and drawn from Glasper, A. and Rees, C. (2013) How to Write Your Nursing Dissertation] The following examples may help you put PICO into practice. Suggestions in the brackets are just extra ideas for what you might want to consider. 1) Isobel is a 45 year old woman who asks you for advice on natural ways of resolving her ...[Examples modified and drawn from Glasper, A. and Rees, C. (2013) How to Write Your Nursing Dissertation] The following examples may help you put PICO into practice. Suggestions in the brackets are just extra ideas for what you might want to consider. 1) Isobel is a 45 year old woman who asks you for advice on natural ways of resolving her ...Jul 7, 2023 · These questions bring together multiple concepts related to a specific clinical situation or research topic. They are typically divided into two categories: Qualitative Questions aim to discover meaning or gain an understanding of a phenomena. They ask about an individual's or population's experience of certain situations or circumstances. If you are planning to create a systematic review, it is usually best to start with a PICO style question, it provides structure and boundaries to the task. Let’s try: To search for the core topics discussed in your review, you are probably going to want to use a combination of approaches. You are probably going to need to use the subject ...You need to assess what reasonable clinical study population your patient could be part of. For example, if your patient is a 73 year old woman, "73 year old women" or "women in their 70s" is too specific because it is highly unlikely that clinical researchers would design a study that would exclusively enroll women in their 70s.Finally, you will click on a button and the PICOT Research Question Generator will present the following: Your PICOT question. Your null and alternative hypotheses. Your independent variable. Your dependent variable. The statistical test used to answer your PICOT question. It should take you less than five minutes to complete the web form below. Appendix H. PICO tables. PICO tables were generated for each question defining the target population, interventions and comparators (where appropriate) and outcomes. These are presented with a summary of the searching activity for each question. Go to: Use the PICOT format to structure your literature search based on a clearly-stated, searchable clinical question. P = Patient Population. I = Intervention or area of Interest. C = Comparison or Control group. O = Outcome.Running head: NSG 410 PICOT RESEARCH QUESTION. P Laboring women delivering in a hospital. Problem: Laboring women are constantly urged to use the lithotomy position, but this can sometimes lead to various labor complications.If you are planning to create a systematic review, it is usually best to start with a PICO style question, it provides structure and boundaries to the task. Let’s try: To search for the core topics discussed in your review, you are probably going to want to use a combination of approaches. You are probably going to need to use the subject ...PICO Question Template Examples. It can be helpful to classify your question based on the clinical domain(s) it falls under. See below for definitions, PICO templates, and example questions from the primary clinical domains: intervention, diagnosis, etiology, prevention, prognosis/prediction, quality of life/meaning, and therapy.The list of PICOT question examples will be incomplete if we didnâ&#x20AC;&#x2122;t mention a question about severe malnutrition. 23. Can antibiotics prevent death and sequelae in kids ...Below are examples of nursing related questions: Intervention/Effect/Therapy PICO Question: An example: In adult patients with total hip replacements (Patient population) how effective is early ambulation (Intervention of interest) compared to bed rest (Comparison intervention) on decreasing post-op DVTs (Outcome)? Note: The question may also ...PICOT 7 PMTCT What is the most effective antiviral therapy during the third trimester of pregnancy, to reduce transmission of HBsAg? P: Pregnant women in the third trimester of pregnancy (defined as 27–40 weeks gestation) with chronic hepatitis B virus infection (positive for HBsAg persistently for more than 6 months) (stratified by HBeAg ...PICO Question Template Examples. It can be helpful to classify your question based on the clinical domain(s) it falls under. See below for definitions, PICO templates, and example questions from the primary clinical domains: intervention, diagnosis, etiology, prevention, prognosis/prediction, quality of life/meaning, and therapy.The list of PICOT question examples will be incomplete if we didnâ&#x20AC;&#x2122;t mention a question about severe malnutrition. 23. Can antibiotics prevent death and sequelae in kids ..."Among women in labor, does the use of labor support/doulas versus no labor support affect labor complications?" (PICOt Question example by M. Montgomery) (PICOt Question example by M. Montgomery) Types of Questions: Therapy, Diagnosis, Prognosis, Harm/Etiology, Prevention, Cost-Effectiveness, Quality of Life.The framework is actually divided into four major elements. A good clinical question will address most, if not all, aspects of the PICO nursing questions. The following are the parameters defined by PICO (T) when it comes to designing of clinical questions: P: Patient, Problem, Population. I: Intervention. Table 2.1, PICO questions for the recommendations in women (the general population of women ...P: laboring women delivering in a hospital I: positions other than the lithotomy position C: lithotomy position O: decreased incidence of assisted deliveries In laboring women delivering in the hospital, do positions other than lithotomy position lead to a decreased incidence of assisted deliveries?PICO Question Examples It will be a time-consuming and difficult venture to identify the most appropriate resources and find relevant evidence without a well-focused question. PICO helps to form a question and facilitate quick and wider literature search.PICO framework helps to identify the main elements of a question and simplify writing a ...This is among the perfect PICOT question examples for falls. 2. The Prognosis or the Prediction. These questions are used in determining the possible complications that arise from a particular condition or the clinical course over a specific time frame. An example of an intervention PICOT questions is as follows:Aug 24, 2023 · PICO (T) Evidence-based practice uses the PICO (T) model for formulating a searchable question. PICO (T) is a mnemonic used to describe the four elements of a good clinical foreground question: P = Population/Problem. How would I describe the problem or a group of patients similar to mine? I = Intervention. Clarifying the key elements of the question is a critical first step toward providing an answer to inform a decision, or for a researcher to frame the research to be done. The PICO (Population, Intervention, Comparator, and Outcomes) model captures the key elements and is a good strategy to provide answerable questions. [1] 100 useful pico questions for nursing research 1. Many toddlers are afraid of needles during vaccinations, is using toys as a distraction for the childrenâ&#x20AC;&#x2122;s pain response ...Components of Pico. P- young adults. I- alcohol consumption. C- no alcohol consumption. O- depression. Exposure: The exposure in this case is alcohol. It is injurious to health and it makes aggressive behavior of people therefore, increasing the level of anxiety. Excessive alcohol intake can interfere with the normal process of development and ... PICO Question Examples It will be a time-consuming and difficult venture to identify the most appropriate resources and find relevant evidence without a well-focused question. PICO helps to form a question and facilitate quick and wider literature search.PICO framework helps to identify the main elements of a question and simplify writing a ...Introduction. Stroke is a medical condition that is caused by the interruption or reduction of blood supply to the brain. This deprives the affected part of brain nutrients and oxygen supply. The biochemical processes are hence stopped, interrupted, or impaired; the brain cells can even die. Further, the condition can also be caused by bursting ...Apr 5, 2023 · Level of Evidence What is a PICO Question? PICO is an acronym used for exploring clinical questions. It serves as a framework for evidence-based practice. P (Problem and Population) What health problem is your selected intervention intended to solve? Identify what population of people will benefit the most from your chosen intervention. "Among women in labor, does the use of labor support/doulas versus no labor support affect labor complications?" (PICOt Question example by M. Montgomery) (PICOt Question example by M. Montgomery) Types of Questions: Therapy, Diagnosis, Prognosis, Harm/Etiology, Prevention, Cost-Effectiveness, Quality of Life.PICO is a popular mnemonic in nursing. P stands for Patient/Problem, I for Intervention, C for Comparison, and O for Outcome. PICOT is used by nursing students to generate answers to seemingly vague questions. PICOT question examples such as “How effective is handwashing in reducing infections?” can be broken down in the following manner:Appendix H. PICO tables. PICO tables were generated for each question defining the target population, interventions and comparators (where appropriate) and outcomes. These are presented with a summary of the searching activity for each question. Go to: Apr 29, 2011 · I need a PICO question over either pregnancy, pregnancy complications, postpartum, newborn, premature newborn, anything along those lines. I know how to make a PICO question so I am not asking that. I am just having trouble with this area and exploring things I could do one over and find articles with. Thanks! The word PICOT is a mnemonic derived from the elements of a clinical research question – patient, intervention, comparison, outcome and (sometimes) time. The PICOT process begins with a case scenario, and the question is phrased to elicit an answer. “The question needs to identify the patient or population we intend to study, the ...About PICO; PICO's Limitations; Case Study. Case: Patient Education; P: Consider when choosing your patient/problem; I: Consider for your intervention; C: Consider for your comparison; O: Consider for your outcome; PICO: Putting it together; PICO Examples; Other Question Frameworks; ResourcesTherapy nursing PICOT questions examples include: 12. Use of negative pressure wound therapy on a diabetic patient with stage iii pressure ulcers compared with standard moist wound therapy. 13. Comparing the risks of developing breast cancer among women who use oral contraceptives with those who use IUDs. 14.Application to PICO. The articles chosen for the analysis related to the PICO question: “In the second stage of labor, what is the effect of laboring down after complete cervical dilation on mother and baby compared with pushing before cervical dilatation is complete?” The population that wasThe framework is actually divided into four major elements. A good clinical question will address most, if not all, aspects of the PICO nursing questions. The following are the parameters defined by PICO (T) when it comes to designing of clinical questions: P: Patient, Problem, Population. I: Intervention. • Discuss the background questions as a group, and look up the answers as needed. • Find the answer to the foreground question, or have everyone write their own PICO question. • Take 5 minutes to look up the PICO answers. • Share the PICO answers and resources used. Different types of clinical questions are suited to different syntaxes and phrasings, but all will clearly define the PICO elements. The definitions and frames below may be helpful for organizing your question: Intervention/Therapy. Questions addressing how a clinical issue, illness, or disability is treated.Aug 15, 2023 · Background questions ask for general knowledge about an illness, disease, condition, process or thing. These types of questions typically ask who, what, where, when, how & why about things like a disorder, test, or treatment, etc. For example. How overweight is a woman to be considered slightly obese? What are the clinical manifestations of ... These questions bring together multiple concepts related to a specific clinical situation or research topic. They are typically divided into two categories: Qualitative Questions aim to discover meaning or gain an understanding of a phenomena. They ask about an individual's or population's experience of certain situations or circumstances.I = Interventions. C = Comparisons. O = Outcomes. Using the earlier example question, we can break it down into a PICO question like this: P = Patient or Problem (young children) I = Interventions (distractions during immunization) C = Comparisons (no distractions/standard care) O = Outcomes (lower pain scores) You may also hear some people use ...When constructing your PICO question, a few important points to bear in mind: Your patient is a member of a population as well as a person with (or at risk for) a health problem . Factors to consider include age, sex, comorbid conditions, past medical history, socioeconomic status or other demographic variables, as these factors may impact your ...Components of Pico. P- young adults. I- alcohol consumption. C- no alcohol consumption. O- depression. Exposure: The exposure in this case is alcohol. It is injurious to health and it makes aggressive behavior of people therefore, increasing the level of anxiety. Excessive alcohol intake can interfere with the normal process of development and ...This section includes the evidence summaries for each key question. It incorporates a summary of the included review for PICO question 1 and the results of the primary reviews (PICO questions 2–6), other relevant evidence (specifically, related guidelines and systematic reviews) and a summary of the evidence-to-decision framework.Diagnostic OR= (a/b)/ (c/d)=742.9. We would need to perform a test accuracy study to answer our question. The participants would get a mammography (index test) and a biopsy to determine the presence of breast cancer (reference test). Each test would yield a positive or negative test result. Preferably, all patients get both tests, without much ...CHAPTER SUB-CHAPTER QUESTION; 3. Problems of the neonate and young infant: 3.1 Routine care of the newborn at delivery: Among healthy newborn infants in low- and middle-income countries (P), does early skin-to-skin contact of the baby with the mother in the first hour of life (I) compared with drying and wrapping (C) have an impact on neonatal mortality, hypothermia or initiation/exclusivity ...Formulate a PICO Question . Answerable PICO Question: In middle-aged adult females with hypertension, are beta blockers more effective than ACE inhibiters in controlling blood pressure? Image: "Dagstuhl 2008-02-01 - 37" by Nic's events is licensed under CC BY-SA 2.0Sep 15, 2022 · P: laboring women delivering in a hospital I: positions other than the lithotomy position C: lithotomy position O: decreased incidence of assisted deliveries In laboring women delivering in the hospital, do positions other than lithotomy position lead to a decreased incidence of assisted deliveries? Jun 14, 2023 · A good PICO will be specific and define terms and outcomes if necessary. A good PICO will investigate something new in terms of diagnosis, etiology, therapy, harm, etc. A bad PICO is usually a background question disguised as a research question. For example, "what are the effects of Prilosec on patients taking immune suppressants" might seem ... Jul 27, 2023 · You need to assess what reasonable clinical study population your patient could be part of. For example, if your patient is a 73 year old woman, "73 year old women" or "women in their 70s" is too specific because it is highly unlikely that clinical researchers would design a study that would exclusively enroll women in their 70s. PICO and 2×2 table for question about test accuracy. Population of interest=women aged 40–74 years without a history of breast cancer. Investigated test result=positive result on mammography. Comparator test result=negative result on mammography. Outcome=breast cancer according to biopsy (or not) View inline.Aug 28, 2023 · Different types of clinical questions are suited to different syntaxes and phrasings, but all will clearly define the PICO elements. The definitions and frames below may be helpful for organizing your question: Intervention/Therapy. Questions addressing how a clinical issue, illness, or disability is treated. Aug 29, 2023 · If you are planning to create a systematic review, it is usually best to start with a PICO style question, it provides structure and boundaries to the task. Let’s try: To search for the core topics discussed in your review, you are probably going to want to use a combination of approaches. You are probably going to need to use the subject ... A PICO question, sometimes written as a PICOT question, comprises several elements: P – Population, patient, problem. I – Intervention. C – Comparison or control. O – Outcome or objective. T – Time frame (optional component). 📚 PICO Question Types. There are 5 key types of PICO questions. Look at the table below to learn more about ...Aug 18, 2023 · PICOT is different from a standard research question because it is a clinical question. It is composed of various elements that create a framework for research that typical research questions do not usually have. The goal or purpose of PICOT is to ultimately intervene in someone's healthcare. Focus on prevention. A strength of a qualitative PICO question is that it can investigate what patient satisfaction looks like, for example, instead of only reporting that 25% of patients who took a survey reported that they are satisfied. When working with qualitative questions, an alternative to using PICO in searching for sources is the SPIDER search tool.PICO is a popular mnemonic in nursing. P stands for Patient/Problem, I for Intervention, C for Comparison, and O for Outcome. PICOT is used by nursing students to generate answers to seemingly vague questions. PICOT question examples such as “How effective is handwashing in reducing infections?” can be broken down in the following manner: What PICO means. P: Population/disease ( i.e. age, gender, ethnicity, with a certain disorder) I: Intervention or Variable of Interest (exposure to a disease, risk behavior, prognostic factor) C: Comparison: (could be a placebo or "business as usual" as in no disease, absence of risk factor, Prognostic factor B ) O: Outcome: (risk of disease ...

The word PICOT is a mnemonic derived from the elements of a clinical research question – patient, intervention, comparison, outcome and (sometimes) time. The PICOT process begins with a case scenario, and the question is phrased to elicit an answer. “The question needs to identify the patient or population we intend to study, the .... Whitney

Formulate a PICO Question . Answerable PICO Question: In middle-aged adult females with hypertension, are beta blockers more effective than ACE inhibiters in controlling blood pressure? Image: "Dagstuhl 2008-02-01 - 37" by Nic's events is licensed under CC BY-SA 2.0Table 2.1, PICO questions for the recommendations in women (the general population of women ...CHAPTER SUB-CHAPTER QUESTION; 3. Problems of the neonate and young infant: 3.1 Routine care of the newborn at delivery: Among healthy newborn infants in low- and middle-income countries (P), does early skin-to-skin contact of the baby with the mother in the first hour of life (I) compared with drying and wrapping (C) have an impact on neonatal mortality, hypothermia or initiation/exclusivity ... PICO: P = population; I = intervention; C = comparator; O = outcome(s)[ref]For further information on the findings of the reviews based on the PICOs presented in this annex, refer to the EtD frameworks in Supplementary material 2.[/ref] Pre-abortion Rhisoimmunization PICO 1: No anti-D administration in unsensitized Rh-negative individuals seeking abortion (see Recommendation 8 [NEW])Oct 15, 2019 · The framework is actually divided into four major elements. A good clinical question will address most, if not all, aspects of the PICO. The following are the parameters defined by PICO (T) when it comes to designing of clinical questions: P: Patient, Problem, Population. I: Intervention. Components of Pico. P- young adults. I- alcohol consumption. C- no alcohol consumption. O- depression. Exposure: The exposure in this case is alcohol. It is injurious to health and it makes aggressive behavior of people therefore, increasing the level of anxiety. Excessive alcohol intake can interfere with the normal process of development and ...PICO 4: Vacuum aspiration for all indications at gestational ages < 14 weeks (see Recommendation 24) PICO question: For a pregnant person seeking induced abortion or treatment for incomplete abortion or miscarriage (i.e. all indications for vacuum aspiration), is provision of vacuum aspiration by a traditional and complementary medicine ...Aug 9, 2023 · PICO Question Template Examples. It can be helpful to classify your question based on the clinical domain(s) it falls under. See below for definitions, PICO templates, and example questions from the primary clinical domains: intervention, diagnosis, etiology, prevention, prognosis/prediction, quality of life/meaning, and therapy. Aug 16, 2023 · 2. Foreground questions are specific knowledge questions . that affect clinical decisions and ; include a broad range of biological, psychological, and sociological issues. Foreground questions are best suited to the PICO model as it captures the essential elements of your information need to help translate that question into a search query. To ... Use the PICOT format to structure your literature search based on a clearly-stated, searchable clinical question. P = Patient Population. I = Intervention or area of Interest. C = Comparison or Control group. O = Outcome.PICO Framework. Without a well-focused question, it can be very difficult and time consuming to identify appropriate resources and search for relevant evidence. Practitioners of Evidence-Based Practice (EBP) often use a specialized framework, called PICO, to form the question and facilitate the literature search. 1 PICO stands for:Develop and revise questions that focus your inquiry. Create a concept map that demonstrates the relationships between concepts. Once you have selected your topic area and reviewed literature related to it, you may need to narrow it down to something that can be realistically researched and answered. In the last section, we learned about asking ...Jul 7, 2023 · These questions bring together multiple concepts related to a specific clinical situation or research topic. They are typically divided into two categories: Qualitative Questions aim to discover meaning or gain an understanding of a phenomena. They ask about an individual's or population's experience of certain situations or circumstances. Finally, you will click on a button and the PICOT Research Question Generator will present the following: Your PICOT question. Your null and alternative hypotheses. Your independent variable. Your dependent variable. The statistical test used to answer your PICOT question. It should take you less than five minutes to complete the web form below.of the PICO components The PICO question is a convenient and conventional format to use when composing good clinical questions to direct an evidence-based search of research literature. PICO stands for Patient, Intervention, Comparison and Outcome; thus, there are four components of a good clinical question based on the PICO format. PICO Question Template Examples. It can be helpful to classify your question based on the clinical domain(s) it falls under. See below for definitions, PICO templates, and example questions from the primary clinical domains: intervention, diagnosis, etiology, prevention, prognosis/prediction, quality of life/meaning, and therapy..

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